ELISA Recombinant Melanoma-derived growth regulatory protein(MIA) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:Q16674 Uniprot Entry Name:MIA_ Gene Names:MIA Species:Homo sapiens () Source:E.Coli Expression Region:25-131aa Sequence:GPMPKLADRK LCADQECSHP ISMAVALQDY MAPDCRFLTI HRGQVVYVFS KLKGRGRLFW GGSVQGDYYG DLAARLGYFP SSIVREDQTL KPGKVDVKTD KWDFYCQ Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:12.1 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using A375 cell line is less than 5 ?g/mL, corresponding to a specific activity of ? 200 IU/mg. Purity:>98% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:Melanoma inhibitory activity protein, Relevance:Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. PubMed ID:7923218; 8550608; 12230496; 15489334; 15340161; 19807924; 22419821; 11331761 Function:Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. Involvement in disease: SubcellµLar Location:Secreted Protein Families:MIA/OTOR family Tissue Specificity:All malignant melanoma cell lines tested and infrequently in glioma cell lines. Paythway: HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:7076 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=646364 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:8190 STRING Database Link:https://string-db.org/network/9606.ENSP00000263369 OMIM Database Link:https://www.omim.org/entry/601340601340601340